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9 The STEP-HFpEF DM randomised controlled trial enrolled 616 patients with obesity (BMI 30 kg/m 2 ) and both HFpEF (LVEF 40%) and T2D

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D) Fluo-4-loaded HEK-GLP-1R cells were challenged with either vehicle control (1% DMSO) or compound 2 (100 M) in the absence or presence of pretreatment with thapsigargin (2 M, 5 min)

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Its not a substitute for statins if you need strong LDL-lowering, but it can be a very useful tool in a broader plan for heart and metabolic health