Side effects reported during the trials included nausea, vomiting, diarrhea, and constipation, but patients characterized these effects as mild and temporary
The review authors suggest that personalized treatment plans can be devised: these plans would consider an individuals genetic makeup, carnitine levels, SLC functionality, and interplay with other transporters/enzymes, offering a more tailored approach to fertility treatment. Key Takeaway Carnitine transport is important in maintaining energy metabolism and supporting reproductive health, including sperm function
Some participants reported mild nausea
For instance, treating 20 type 2 diabetics with 35 mg PLP along with 3 mg activated folate and 2 mg vitamin B12 improved skin sensation in diabetic peripheral neuropathy (Walker 2010)
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
Hemmings HC, Egan TD, eds