Including protein in smaller breakfasts may help some people spread their intake more gradually throughout the day
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As may be expected, mean diabetes duration tended to be longer in patients receiving a greater number of background medications, ranging from 7.2 to 10.6 years in patients on metformin monotherapy to 8.4 to 17.3 years in patients receiving more than one background medication
Because the majority of the -cells do not express GLP-1R, and also because GLP-1 inhibits glucagon secretion even in T1D patients with low insulin pancreatic reserve, the mechanism by which GLP-1 decreases glucagon secretion is still a matter of debate [15]
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Am Fam Physician 2008;77:1431-1436