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Confounding by obesity (which itself increases autoimmune risk)

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As an example of a combined GLP-1 + FIM intervention, eligible patients could receive both GLP-1 therapy and a FIM intervention emphasizing foods to support weight maintenance, reduce side effects, minimize loss of muscle and bone mass, and promote nutrient adequacy

Importantly, these studies demonstrate a consistent pattern: whilst retained gastric contents are significantly more common in GLP-1 RA users, the absolute rates vary considerably depending on patient factors, medication duration, and assessment methods [35]