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These metabolic changes may precede or contribute to neuroinflammatory and cognitive alterations over a longer duration, suggesting that extended WD exposure or pre-existing metabolic vulnerability could amplify these effects

As GLP-1s have moved towards weekly dosing, users are less likely to experience the desensitisation that comes from repeated exposure

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Morphologically, significant reduced taste bud abundance was observed in obese mice while no differences in size or a change in balance between type I, II, and III cells was observed

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