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35 Although these CVOTs were not specifically powered to detect differences in HF outcomes, they provided the first valuable signs of the benefit of GLP-1RAs in patients with HF

Healthspan uses GLP-1s as a longevity and metabolic health toolnot just for weight loss

Figure 27: Photograph of Sir James Black (1924-2010), credit: Lyall

Stronger cardiovascular data: The SELECT trial provides robust evidence for cardiovascular protection

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Finally, we identified six papers describing favorable associations between GLP-related molecules (that is, geniposide, GLP2, puerarin) and reductions in depression-like behavior 170,171,172,173,174,175