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The difference reflects population: TRIUMPH-4's osteoarthritis cohort was older and more comorbid

Combination therapies (GLP-1s with other peptides, metabolic drugs, or lifestyle protocols like the ProLon Fasting Mimicking Diet ) are already being studied to push results even further

In addition, the reductions in A1C and FPG with JANUVIA compared to placebo were generally similar to those observed in other monotherapy studies

BMI, Body mass index