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The activation of caspases in response to oxidative stress was closely linked to the observed reduction in aminophospholipid translocase activity and the increased PS externalization in aged RBCs

Regarding FDA approval: because this is a compounded product, it is not directly FDA-approved

doi: 10.1007/s10658-011-9920-1 51 KozlovaL

For clinics and pharmacies operating in that gap, the cost of getting the call wrong has not gone down

This allows for targeted local or systemic effects

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