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ALC supplementation significantly reduced plasma TC and LDL-C levels in HCD-fed mice and attenuated atherosclerotic progression in LDLR / mice
In contrast, we found that these metabolomic alterations led to a reduction in the plasma level of different metabolites including uridine, thymine, carnosine, theophylline, aspartate, taurine, serine, glutamate, tryptophan, arginine, and 53 other metabolites in the acute patients compared to HCs ( Supplementary Figures 6A, B )
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A., Long, F
341 The PARylation is also markedly increased in muscle and the liver of aged mice in parallel with robustly decline of NAD + levels
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