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JAMA Psychiatry , 82(1), 94-98

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Tirzepatide is the first dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, structurally based on native GIP rather than exendin-4

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NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer