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doi:10.1056/nejmoa2403347 4.Shor R, Mihalache A, Noori A, et al

Any discrepancies were resolved by consensus or by the third reviewer (Chen)

Dry Eye Syndrome (DES) Dry eye syndrome (keratoconjunctivitis sicca) occurs when the eyes do not produce enough tears or when tears evaporate too quickly, leading to inflammation and damage to the eyes surface