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When AOD 9604 binds to beta-3 adrenergic receptors on white fat cells, it triggers a cascade that starts with adenylyl cyclase activation

Patients with pre-existing peripheral neuropathy might report changes in sensation during treatment

Many patients start weekly or biweekly for the first month, then shift to a maintenance schedule every 24 weeks

A medical consultation is mandatory before treatment and must be completed at least 48 hours in advance

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Vitamin B12 is essential for normal fetal development, and a deficiency should be corrected