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Ang R, Mastitskaya S, Hosford PS, Basalay M, Specterman M, Aziz Q, Li Y, Orini M, Taggart P, Lambiase PD

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Similarly, incretin-like actions of GIP may also proceed indirectly through amino acids and potentiation of GIPR-dependent stimulation of glucagon secretion from alpha cells [47]

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While the relationship between IGF-1 signaling and longevity is complex, with both positive and negative effects saw depending on context, research with IGF1 LR3 has helped clarify the specific effects of receptor start independent of the complex control mechanisms that govern native IGF-1

All values were converted to cAMP concentration using cAMP standard curve performed parallel and data were subsequently normalised to the response of 100 M forskolin in each cell line, and then normalised to the WT for each agonist