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The right approach is the one that's safe, sustainable, and supports your overall health, not just the number on the scale.

The Bottom Line GLP-1 agonists are powerful and effective medications for Type 2 diabetes and obesity

Januvia is taken orally once daily, typically at 100mg making it convenient for patients who prefer pills over injections

The unit calculations produce clean, round numbers at the most common doses

After 4 weeks, the dosage is increased to 5mg injected once-a-week

Peer review Peer review information Nature Medicine thanks Louis Aronne, Carina Oehrn and the other, anonymous, reviewer(s) for their contribution to the peer review of this work