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This range is higher than the standard 0.8 g/kg for sedentary adults because semaglutide therapy creates a unique metabolic environment where your body is simultaneously losing fat and at risk for muscle breakdown

Tissues were immediately deep frozen in liquid nitrogen, and stored at 80 C until used

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Recently report address that GH inhibits DNA damage repair by suppressing ATM and DNA-PKcs activities in colon cells, leading to decreased DNA repair by both HR and NHEJ (Chesnokova et al., 2019)

Obstructive sleep apnea particularly relevant given the FDA's December 2024 approval of tirzepatide specifically for obesity-related OSA also qualifies as a relevant comorbidity for patients in the BMI 27 to 29.9 range