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In the CY 2023 OPPS/ASC final rule with comment period, we finalized the proposal in section XI., CY 2023 OPPS Payment Status and Comment Indicators, to add a new definition to status indicator A to include unclassified drugs and biologicals that are reportable with HCPCS code C9399 (87 FR 72051)

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For multi-dose vials, bacteriostatic water is strongly preferred

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The review also describes evidence from preclinical and clinical studies on targeting novel non-VEGF angiogenic pathways in breast cancer and several approaches to the normalization of tumor vasculature by targeting pericytes, utilization of microRNAs and extracellular tumor-associate vesicles, using immunotherapeutic drugs, and nanotechnology