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Some people report mild stomach upset or nausea when taking L-carnitine on an empty stomach

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Patients should be advised to seek medical attention if they develop signs or symptoms suggestive of gallbladder disease, such as right upper abdominal pain, fever, or jaundice

However, since no measurements of splanchnic hemodynamic changes after more long-term exposure to GIP receptor antagonism have been conducted, in either animal models or humans, the therapeutic implications of this effect are uncertain

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In response to the UK regulator's warning, 'Novo Nordisk', the manufacturer of Wegovy and Ozempic, stated, "We recommend that patients only use these medications for their approved indications and under the strict supervision of a healthcare professional." 'Eli Lilly', the manufacturer of Mounjaro, said, "The Mounjaro patient information leaflet specifies that acute pancreatitis is an uncommon side effect that may affect up to 1 in 100 people." The MHRA plans to conduct a separate study on patients using GLP-1 class drugs