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Clinical implications: Recurrent bacterial vaginosis may indicate the need for microbiome assessment before ART Gut dysbiosis contributes to insulin resistance and inflammatory states, affecting ovulation Antibiotic exposure timing may impact fertility treatment outcomes Therapeutic considerations: Evidence supports treating confirmed infections before conception attempts, optimizing dietary fiber diversity, and considering targeted probiotic interventions for recurrent BV in fertility contexts

Both TLYYL and TLYYH treatments significantly attenuated this DSS-induced upregulation of pro-inflammatory cytokines

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10.1136/gutjnl-2017-314759 115 SungH.FerlayJ.SiegelR