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Liver disease data from SYNERGY The SYNERGY MASLD trial could be the most commercially significant readout

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In August 2024, the Pharmacy Quality Assurance Commission (commission) issued the following statement on compounding semaglutide, which is still current: The federal Food Drug & Cosmetic Act (FD&C Act), prohibits compounding regularly, or in inordinate amounts, any drug products that are essentially copies of a commercially available drug product. The FD&C Act and the FDA have recognized that a compounded drug will not be considered a copy of a commercially available drug product in the following three situations: The drug has been discontinued and is no longer marketed

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Gene 819 , 146265 (2022)

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However, the AUC of the victim drugs were not altered by GLP-1 RA administration in most cases, suggesting that clinically significant DDIs are unlikely to occur

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