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Purine catabolism: links to mitochondrial respiration and antioxidant defenses

Nov 5 2019;25(6):673-693

The article recommends ophthalmology clearance before starting GLP-1 therapy for anyone with known diabetic eye disease, plus periodic follow-up afterward

However, a recent study has shown that in order to lethally impact the peroxidation process, PUFAs must be activated and integrated into phospholipids (PLs), a form of membrane lipid, and that free fatty acids cannot trigger ferroptosis

p=0.02) ( Figure S3 )