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In contrast, plasma membrane recycling of internalised GLP-1R V229A was increased versus WT at both 1-hour and 3-hours recycling periods (Figure 6D, E), while no changes in exendin-4-induced GLP-1R degradation were detected between GLP-1R WT and V229A (Figure 6F, G)

PLoS ONE 7 , e48175 (2012)

To that end, internists and other (largely OB/GYN and cardiology) specialists are adding GLP-1s to their prescribing and growing quickly within the prescribing pool

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