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While semaglutide has not been studied in a dedicated OSA trial of this scale, the weight loss it produces likely offers similar benefits, since the primary mechanism is fat reduction around the airway and abdomen

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For someone who preserved 10 additional pounds of muscle compared to a person who lost the same body weight but with higher lean mass loss, that represents roughly 60 extra calories burned per day, or over 20,000 extra calories per year, without any additional effort

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Standard subcutaneous injection guidance from Memorial Sloan Kettering Cancer Center (MSKCC) recommends avoiding the area immediately around the navel, where tissue is denser and injections are more uncomfortable

PLoS Computational Biology , 15, e1006844