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Specifically, starting from a closed conformation in apo state, the ECD of GLP-1R bound by either compound 2 or truncated peptide agonist (peptide 5) 10 rotated clockwise and approached to ECL1 and ECL2

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Specifications Purity: 99% (RP-HPLC, each component) Identity: MS-verified Form: Lyophilised powder, sealed vial Storage: 20 C, protected from light Manufacturer: Oxford Research Syndicate Ltd Batch / Lot: supplied on COA For in-vitro laboratory research use only