All patients received their previously established dose of metformin throughout the study
The expression of MOTS-c is age-dependent and has been detected in multiple tissues, including skeletal muscle, T cells and in systemic circulation 6,7,8,9,10 and the pancreas 7,11
It is commonly studied for its interaction with the growth hormone secretagogue receptor (GHSR-1a), making it a frequent subject in metabolic, regenerative, and endocrine research models
(4-5 .
It regulates blood sugar levels by mimicking a hormone called GLP-1 that your body naturally produces

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