Dual GIP/GLP-1 agonists now represent the highest-revenue growth segment in the GLP-1 weight loss drug market at 18.4% CAGR , with tirzepatide generating USD 18.3 billion in 2025 revenue through Zepbound and Mounjaro surpassing Eli Lillys entire insulin franchise within two years of commercial launch
Regardless, both medications require long-term use to maintain weight loss, and a commitment to healthy lifestyle changesincluding dietary changes and increased physical activityis necessary to achieve the best results
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If these symptoms worsen or become troublesome, contact your GP Body weight : Regular weight monitoring helps assess the effectiveness of your diabetes treatment and can identify unexpected changes Retinal screening : If you have pre-existing diabetic retinopathy, arrange appropriate monitoring as rapid improvements in blood glucose can sometimes temporarily worsen retinopathy When to seek urgent medical help: Severe, persistent abdominal pain (with or without vomiting) contact NHS 111 or seek emergency care (999) as this could indicate pancreatitis or gallbladder disease Signs of dehydration or ketosis due to persistent vomiting or diarrhoea Sudden changes in vision Symptoms of hypoglycaemia (if you are also taking insulin or sulfonylureas) Maintain open communication with your healthcare team about all aspects of your treatment, including any supplements you are taking
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