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In Phase 2 trials, treatment with survodutide led to greater reductions in both HbA1c levels and body weight compared to placebo after 16 weeks

Furthermore, previous studies have found an increase in lipid content of the soleus muscle but not the tibialis in the off-spring of subjects with type II diabetes [12] and Indian males with diabetes have significantly higher IMCL-content in the soleus compared to healthy controls [38]

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