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Environ Toxicol Pharmacol

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For skin lightening treatments and brightening Glutathione prevents the activation of Tyrosinase (the first step in melanin production) by reducing free radicals in the body that can activate it and cause an increase in melanin production

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Interestingly, the nuclear GSH pool appears to be dynamic and independent of cytosolic GSH, undergoing major shifts in relative concentration throughout the cell cycle which reaches upwards of four times the concentration found in the cytosol [76]