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639 Despite early study termination (clinical hold) by the US Food and Drug Administration, fulranumab treatment resulted in dose-dependent efficacy and was generally well tolerated

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For instance, while quercetin has been reported to activate both enzymes, curcumin has shown potential as an activator of SIRT1, promoting its deacetylase activity and contributing to anti-inflammatory effects 178

Glutathione can contribute to anti-aging efforts by reducing oxidative stress and inflammation, which are factors in the aging process

10.3892/etm.2020.9473 6 ChenY.FangZ

10.1371/journal.pone.0049418 126 LiuM.LiangK.ZhenJ.ZhouM.WangX.WangZ.et al (2017)