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The impact of hypoxia on cytosolic NADP redox dynamics had remained less clear, since lack of oxygen as an electron sink causes metabolic reduction, but also boosts H 2 O 2 production and glutathione oxidation in different phases of the hypoxic episode [37]

MiquelSChampCDayJAartsEBahrBABakkerMet al

CHKA and EBP showed lower expression in COPD samples than in controls, whereas CHRM3, NCSTN, and RPS6KA5 were increased in COPD samples ( Figure 10A )

however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects

Alway, S

El glutatin reducido choca contra la barrera hematoenceflica y por tanto difcilmente llega hasta las neuronas del cerebro (3)