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PMCID: PMC7416373

Ultrasound Assisted Liposuction (Vaser) Vaser liposuction is able to remove fat close to the muscle by utilising sound energy to break the fat deposits apart

This is compatible with an autosomal dominant inheritance with incomplete penetrance (38) in which an affected parent has a 50% chance of passing lipedema to their child

Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells

Additional promising approaches target immune checkpoint pathways, receptor-interacting protein kinase 1, and intracellular signaling cascades

Contributed reagents/materials/analysis tools: AJM KB