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With a vitamin B12 deficiency comes the risk of suffering from megaloblastic anemia, including symptoms of fatigue, weakness, pale skin, lack of appetite, infertility, and unexplained weight loss

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At the high end, switching from a 5 mg vial to a 60 mg vial can cut your per-milligram cost by more than half

Variants in GST enzymes, MTHFR, and antioxidant response genes may reduce your body's natural glutathione synthesis or recycling efficiency, potentially increasing supplementation needs

Hepatic or renal impairment these are compounds handled by the liver and kidneys