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EAAT1 (glutamate-aspartate transporter, GLAST) and EAAT2 (glutamate transporter-1, GLT-1) are expressed in glial cells and involved mainly in synaptic glutamate clearance, while EAAT3 (excitatory amino acid carrier 1, EAAC1) is expressed in mature neurons and involved in cysteine uptake rather than in glutamate clearance in the brain

If the body learns to rely on an exogenous source, it could potentially stop producing it on its own, therefore when you go off the drugs it could potentially make the problem worse than when you started

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However, keeping track of your symptoms can help you and your healthcare provider determine whether your response requires further investigation