Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway
Accurate mass measurement ensures reliable analytical results
The results revealed that gingerols and shogaols might have the potential to be developed as NLRP3 inflammasome-mediated IL-1 secretion inhibitors for the prevention of NLRP3 inflammasome-associated diseases (Ho and Chang, 2018)
Notably, GLS-mediated deamination of glutamine to glutamate is the first and rate-limiting step of glutaminolysis, making it an attractive druggable target 9
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Furthermore, there is already extensive experience in the use of both drugs as initial therapy for PV, with results that appear to be comparable to that of hydroxyurea, as discussed above in the previous section