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Moreover, GLP-1 receptor agonist use was also associated with significantly lower cartilage-loss velocity in the medial femorotibial joint (adjusted mean difference, 0.02 mm

This is called backloading

Not exhaustive, but highly practical

Tirzepatide and cardiovascular disease A previous study has shown that tirzepatide can protect human cardiomyocytes by effectively ameliorating apoptosis, fibrosis, and hypertrophy when exposed to high glucose

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Key Takeaways Tesamorelin reduces visceral adipose tissue by 1218% over 6 months in clinical trials, but the effect is compartment-specific