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Previous studies have found that age was a factor in determining carnitine level ( Carnitine in Bipolar Disorder Bipolar disorder (BD) is a chronic mental illness characterized by severe bipolar changes, ranging from extreme excitement or mania to severe depression

Methods: This retrospective cohort study utilized the TriNetX platform, selecting adults (18 years) with RA, obesity (BMI 30 kg/m), and no history of diabetes mellitus

Lower doses produced more modest reductions: 4 mg dose: approximately 8.7% mean weight reduction 0.5 mg dose: approximately 2.0% mean weight reduction Placebo: a small mean weight gain of approximately 2.0% Readers should note that these figures are drawn from a single phase 2 trial with a relatively small sample size and 24-week duration