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According to Harvard Health, rarer but more serious side effects can include inflammation of the pancreas, called pancreatitis

The article says semaglutide commonly causes nausea, vomiting, and constipation, which are the same gastrointestinal symptoms many antibiotics can trigger independently

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Secreted from the Lcells in the small intestine, glucagonlike peptide (GLP)1, an incretin hormone lowers blood glucose levels by stimulating insulin and inhibiting glucagon secretions in a glucose level dependent way from the pancreatic islets [12]