Recently, various types of drug delivery systems based on blood cells have been developed, as well as blood-cell-inspired carriers that mimic the features of native blood cells (Wang et al., 2022)
While global Nrf2 activation may be beneficial, its specific effects in different cell types (e.g., potentially promoting ferritinophagy in macrophages) require careful consideration
Certain clinical scenarios might warrant a more gradual approach to discontinuation, even though not pharmacologically necessary
GLP-1 receptor agonists (like Wegovy and Mounjaro) have gained global attention for their ability to help people shed significant weight
[10] Ironically, sedentary people actually eat more than lightly active people because they have less sensitivity to satiety signals due to inactivity
Ital J Pediatr 50 , 18 (2024)