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The authors noted that existing data come from separate trials of each form of semaglutide

Furthermore, extensive clinical trials with Ozempic have revealed significant cardiovascular benefits, including a reduced risk of major cardiovascular events, such as heart attacks and strokes, in patients with type 2 diabetes who have cardiovascular risk factors

This is one of the most common reasons patients transition between these medications

Efficacy and safety of mazdutide in Chinese patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 2 trial

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Like any other medicine, retatrutide can cause some side effects