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Product label: ACETADOTE (acetylcysteine) injection, solution [ Cumberland Pharmaceuticals Inc.] Last revised: January 2011 [DailyMed] Clinical reviews Oxidative stress has been implicated in the pathogenesis and progression of chronic obstructive pulmonary disease

Moreover, many kelch-like ECH-associated protein 1 (Keap1) mutations or loss of heterozygosity in the Keap1 locus have been identified in lung cancer cell lines or cancer tissues [261, 262]

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