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[7] Epithalon's dual action on hTERT expression and melatonin synthesis may therefore represent two arms of a coordinated intervention: direct telomerase reactivation through chromatin remodeling, and indirect stabilization of telomere dynamics through restoration of circadian-regulated DNA repair and oxidative defense

In the DSM-IV, the disorder was classified within the broader category of pervasive developmental disorders, with specific diagnostic criteria involving social, communicative, and behavioral impairments