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It is a drug that has dominated headlines, first as a medication for type 2 diabetes, then as a weight-loss aid

Detecting monogenic obesity: a systematic exome-wide workup of over 500 individuals

10.1056/NEJMoa2312323 [DOI] [PubMed] [Google Scholar] Mller T., Finan B., Bloom S., DAlessio D., Drucker D., Flatt P., et al

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Since cells rely on the NAD + salvage pathway as the main source of NAD + , we have focused on the role of this pathway in cancer