This usually means a BMI of 30 or higher
Once the drug is present on the skin surface, it can diffuse through the epidermis through two routes, either transepidermal(transcellular or intercellular) or transappendageal(sweat ducts, hair follicles, and pilosebaceous glands) [311]
Regular use helps reduce dullness, enhances clarity, and promotes a visibly brighter and even-toned complexion
In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)
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