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The present study therefore aimed to perform a detailed characterization of disease progression, tumor burden, and HCC histological and molecular classification in GAN DIO-NASH mice

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A blockage of ascorbate accumulation in response to high light was also observed when glutathione deficiency was induced pharmacologically by buthionine sulfoximine treatment, providing extra evidence that, in high-light conditions, glutathione acts as a substitute for ascorbate reduction (Figure 1)