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In addition, other RBC mechanical stability tests, like the Couette type ektacytometer, have been suggested to detect sub-hemolytic damage [236]

In one comparative study of the toxicity of carbon black, single-wall carbon nanotube, silicon dioxide (SiO 2 ), and ZnO NPs, ZnO induced the most remarkable cytotoxicity by promoting intracellular oxidative stress, whereas SiO 2 NPs mainly induced DNA damage (Yang et al., 2009)