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The bifunctional enzyme, formimidoyltransferase cyclodeaminase (also called glutamate formiminotransferase), then transfers the formimino group from N -formimidoyl-L-glutamate (commonly referred to as FIGLU) to THF yielding N 5 -formimino-THF (5-fominino-THF) and glutamate

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However, for some, there is a dark side to semaglutide that includes high costs, medication shortages and the potential for severe side effects

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doi:10.1097/chi.0b013e31815a56f1