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Semaglutide may be a valuable tool in this process, but it works best when combined with healthy lifestyle choices and ongoing medical support

Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer: The Womens Health Study

Tricyclic antidepressants (TCAs) such as amitriptyline are associated with weight gain and potential insulin resistance, which may counteract the glucose-lowering effects of Ozempic

The full text is on the Nature website at doi.org/10.1038/s41586-026-10444-4

Blau N, Duran M, Gibson KM, Dionisi-Vici C (2014) Physicians guide to the diagnosis, treatment and follow-up of inherited metabolic diseases