group has received funding from the European Research Council (ERC) under the European Unions Horizon 2020 research and innovation programme (grant agreement 851647), the BBVA Foundation (Ayudas Fundacion BBVA a Proyectos de Investigacion Cientifica 2021 - Proyecto CoralCellSeq), and the Spanish Ministry of Science and Innovation (PID2021-124757NB-I00 funded by MCIN/AEI/10.13039/501100011033/ FEDER, UE)
Pharmacologically, it is activated by the endogenous incretin hormone GLP-1 as well as by therapeutic agonists such as exenatide, liraglutide, semaglutide, and dulaglutide, which are widely used to treat type 2 diabetes and obesity
It belongs to a class called acylated peptides, where a fatty acid chain is chemically attached to the peptide backbone
Prevalence of atherosclerotic risk factors and the metabolic syndrome in patients with chronic inflammatory arthritis
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GLP-1 stands for glucagon-like peptide-1, a natural hormone your body produces in the gut