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[8] Once activated, these G-proteins may stimulate the production of second messengers like cAMP or IP3, which appear to act as secondary signaling molecules, potentially further propagating the signal within the cell

J Physiol 591(17):40874097

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Oral Bioavailability Enhancement of Docetaxel by Preparation of Freeze-Dried Ternary Solid Dispersion Using Hydrophilic Polymer and Surfactant

Further, animal studies indicate that it may strengthen the gut-brain axis, improving feedback between the GI tract and the central nervous system to elicit systemic effects [2, 4, 11]

Half of patients reported significant symptom improvement