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(By comparison, Novo Nordisks best-seller Wegovy/Ozempic brings in similar multi-billion revenues, but Lillys CAGR in recent quarters has been higher.) Analysts attribute Lillys success to tirzepatides superior weight loss in trials and aggressive marketing

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Animals also presented a reduction of tight junction protein ZO-1, suggesting other effects into BBB, and exhibited augment in lipid peroxidation in the brain [29]