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10.1038/ncomms5196 199 WeissJ

However, several limitations should be acknowledged

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[] Each included child had three teeth fulfilling the inclusion criteria which were allocated based on computer-generated random numbers by an individual who is not involved in the study to three different treatment groups Group I 38% SDF only (control)

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224 In general, the evidence is suggestive for the benefits of EPA/DHA in migraine, but until better quality clinical trials are available that account for the limitations mentioned above the clinical benefit remains unclear